Ultra early screening of tumors
Utilizing innovative technology to care for life and health, assisting in early detection of cancer
Committed to becoming a precision diagnostic industry
Leader of
Leader of
Committed to be the
leader in the industry
Shenzhen Youshengkang Biotechnology Co., Ltd. was founded in 2015 and is a biotechnology high-tech enterprise jointly founded by Chinese and American scientists and entrepreneurial teams.
Focusing on in vitro molecular diagnosis, integrating product research and development, production, marketing, and services, we have established a complete industrial chain in the field of molecular diagnosis.
35 invention and utility model patents have been declared and 19 have been authorized.
The main business includes three major fields: in vitro diagnostic reagents, medical laboratory analyzers, and medical testing services.
The company's in vitro diagnostic reagent products are based on three major technological platforms: genetic testing,
immune testing, and cytology,
Covering fields such as early screening of tumors, individualized diagnosis of tumors,
cardiovascular and metabolic diseases.
Focusing on in vitro molecular diagnosis, integrating product research and development, production, marketing, and services, we have established a complete industrial chain in the field of molecular diagnosis.
35 invention and utility model patents have been declared and 19 have been authorized.
The main business includes three major fields: in vitro diagnostic reagents, medical laboratory analyzers, and medical testing services.
The company's in vitro diagnostic reagent products are based on three major technological platforms: genetic testing,
immune testing, and cytology,
Covering fields such as early screening of tumors, individualized diagnosis of tumors,
cardiovascular and metabolic diseases.
Specializing in precise medical treatment of tumors,
providing the most clinically valuable Genetic testing services
providing the most clinically valuable Genetic testing services
3
In vitro diagnostic reagents
Medical laboratory analyzer
Three major areas of medical testing services
Medical laboratory analyzer
Three major areas of medical testing services
42
Declared inventions and utility models
42 patents
42 patents
28
Declared inventions and utility models
Authorize 28 items
Authorize 28 items
Internationally leading molecular detection technology
Efficient circulating tumor DNA enrichment and extraction system
Blood contains a large amount of free extracellular nucleic acid (cfDNA), including not only nucleic acid from tumors (ctDNA), but also nucleic acid from other sources. Due to the low concentration and high fragmentation of ctDNA, enrichment and separation are particularly important. The Youshengkang high-efficiency circulating tumor DNA enrichment and extraction system optimizes the magnetic beads, active groups, and processing conditions to concentrate the extracted ctDNA fragments within the 170bp range, which is different from the large molecular genomic DNA released in the blood due to cell fragmentation, providing quality assurance at the source for subsequent PCR and NGS detection.
Ultra sensitive ARMS gene amplification technology
ARMS technology utilizes specific primers for high-precision PCR amplification of mutated target sequences. At the same time, probes are used to detect amplified products, and rare mutations in sample DNA are detected on a real-time fluorescence quantitative PCR platform to achieve high specificity and sensitivity in gene mutation detection. On the basis of ARMS-PCR, Youshengkang has been optimized and improved to detect low-frequency mutations as low as 0.2% (close to 3 copies) in samples, close to the level of digital PCR, while maintaining cost unchanged. The detection cost is only 1/10-1/5 of digital PCR.
Double stranded gene methylation detection technology
DNA methylation is the process of selectively adding methyl groups to cytosine under the action of DNA methyltransferase (Dnmt) to form 5-cytosine, and is an important epigenetic marker. Due to the fact that DNA methylation is found in almost all cancers and occurs before or in the early stages of cancer, it has become an ideal marker for early cancer diagnosis. The double stranded gene methylation detection technology developed by Youshengkang, which designs primers for DNA double stranded molecules separately, can effectively improve the detection rate, high sensitivity, and specificity compared to only detecting single stranded molecules.
Targeted Encoding Library Construction (NGS) Technology
The development of flux sequencing technology has brought about a gradual reduction in sequencing costs. Compared with whole genome sequencing, capture sequencing can isolate and enrich regions of interest, and is widely used in fields such as genetic mutation, tumor screening, and concomitant diagnosis. Compared to ordinary multi PCR library building techniques, capture sequencing can more accurately detect information about specific region sequence changes, especially improving the detection rate of low-frequency mutations. The Youshengkang targeted capture database building system is improved on traditional hybrid capture methods to improve the capture specificity and uniformity of the target area. By combining big data mining to screen industrializable pan cancer biomarkers, develop products for early tumor screening and personalized medication guidance.
